Tumors often do not respond to chemotherapy because they contain large poorly vascularized areas that limit the efficacy of radiation and chemotherapeutic drugs. In November 27 Proceedings of the ...

When spores of the anaerobic bacterium Clostridium novyi-NT are systemically injected into animals, they germinate exclusively within the hypoxic regions of cancers. The germinated bacteria destroy ...

Cancer cells are clever. Researchers characterize them as wily, smart, sneaky, and stubborn. But what cancer cells are not is impervious to damage and even death by targeted assault, which is why ...

Interferon-γ (IFNγ) has a crucial role in immunity against intracellular pathogens. Approximately 2,000 host genes are induced by this cytokine but the functions of many of these genes remain ...