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Tanita Astra on Instagram: "1️⃣For a long time, a faulty gene was considered a life sentence. If the problem was written into the genetic code, medicine could only manage symptoms, not the cause. Direct DNA editing always carried serious risks, because any mistake became permanent. That’s why most genetic interventions stayed theoretical rather than practical. 2️⃣The main obstacle was irreversibility. Once DNA is cut or altered, there is no easy way back. Scientists needed a method that could in
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Daily CRISPR Updates on Instagram: "Researchers have mapped crucial DNA switches in astrocytes, brain support cells connected to Alzheimer’s disease. They used CRISPRi and single-cell RNA sequencing to investigate nearly 1,000 enhancer candidates in human astrocytes. The team identified 150 functional enhancers that control genes related to Alzheimer's. Their findings provide a framework for understanding genetic factors in neurodegenerative diseases, emphasising the need for similar studies in
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